Yashtimadhu (Glycyrrhiza Glabra)

Yashtimadhu (Glycyrrhiza Glabra) has been conventionally used by Ayurveda in the treatment of respiratory and digestive disorders. It is considered to be a "Rasayana". Mulethi uses specifically include treatment of chronic acidity, ulcers and chronic bronchial conditions. Investigations observed that licorice activates ulcer healing.it also use for  antioxidant, anti-stress properties.
Studies have shown this herb to have the following actions:-
Hormonal Regulator: The phytoestrogenic compounds present in mulethi roots exert valuable action against women hormonal imbalance problems and menopause symptoms like hot flashes & exhaustion, mood swings, etc. It is also help in cortisol production and relieving premenstrual issues like nausea and menstrual cramps.

Glycyrrhizin inhibits immediate airway constriction, airway hyperreactivity, lung inflammation and infiltration of eosinophils with its glucocorticoid-like effect.

Anti-inflammatory and soothing:
Mulethi attenuates the inflammation of bronchi and soothes respiratory tract by inhibiting prostaglandins and histamine secretions, thus it helps in bronchitis.

Glycyrrihizic acid down-regulates the expression of latency associated nuclear antigen (LANA) in B lymphocytes. This causes natural cell death (apoptosis) of the viruses.

Flavonoids, especially chalcones, in yastimadhu decrease expression of bacterial genes, inhibiting bacterial growth and reducing the production of bacterial toxin.

Immune Modulator:
Yashtimadhu has excellent immunostimulant properties it activate T lymphocyte proliferation and significantly reduced expression of proinflammatory cytokines, such as nuclear factor–κB, interleukin-1β and interleukin-6.

Skin Lightening:
Glabridin in yastimadhu inhibits tyrosinase activity and interrupt with excessive melanin production, thereby inducing skin lightening

Yashtimadhu is a peripheral anti-tussive and demulcent, it inhibits cough reflex by reducing bronchial mucosal irritation.