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Heptovit® SGC and Syrup - Mode of Action
  1. Zingiber officinale (Soonth) - Anti oxidant and Hepato-protective action
    The study concluded that the hepatoprotective effect of aqueous ethanol extract of Z. officinale against acetaminophen-induced acute toxicity is mediated either by preventing the decline of hepatic antioxidant status or due to its direct radical scavenging capacity.
    (Food Chem Toxicol.  2007 Nov;45(11):2267- 72.)
     
  2. Fumaria parviflora (Pittapapda) - Choleretic and cholagogue
    Fumaria parviflora extract exhibits a selective protective effect against paracetamol-induced hepatotoxicity, probably mediated through MDME inhibition.
    (Gen Pharmacol.1996 Sep;27(6):979-83)
     
  3. Boerrhavia diffusa (Punarnava) - Brings down elevated liver enzymes
    The elevated level of serum and liver alkaline phosphatase after radiation exposure was reduced in the B. diffusa-treated group. The serum and liver glutamate pyruvate transferase, which were elevated after radiation exposure, were also reduced by treatment with B. diffusa compared to the control.
    (Integr Cancer Ther .2007 Dec;6(4):381-8)
     
  4. Andrographis paniculata (Kalmegh) :– Activated antoxidant enzymes
    The study indicates that the antioxidant effect of andrographolide could be due to its ability to activate antioxidant enzymes that catalyze the reaction of oxidants and are effective in severe liver damage.
    (Integr Cancer Ther 2007 Sep;6(3):271-80)
     
  5. Phyllanthus niruri (Bhuiamla) :– Anti viral and hepatoprotective
    NIM administration (8 mg/kg body wt) for 7 days caused significant deplete on of the levels of SOD, CAT and reduced GSH, along with the increased levels of lipid peroxidation. Intraperitoneal administration of the extract at a dose of 50 mg/kg body wt for 7 days, prior to NIM treatment, significantly restored most of the NIM-induced changes.
    (Indian J Biochem Biophys 2006 Oct;43(5):299-305)